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After two invigorating days of plenary discussions and scientific presentations, the Second International Congress of Urologic Research and Education on Underactive Bladder (Cure-UAB) came to a successful conclusion on 4 December 2015.
There was great enthusiasm among delegates, healthcare professionals, industry and society participants. CURE-UAB is considered the biggest international conference on Underactive Bladder and achieved several important outcomes with potential long-term impact on the ground.
CURE-UAB sent a strong message of the international community’s commitment towards diagnosis and management of Underactive Bladder Syndrome. Also highlighted during the Conference was the message that working towards cure is a shared mission for all and that partnerships are critical in pursuing the cure for Underactive Bladder Syndrome.
Here are a few highlights of the presentations made during CURE-UAB:
The Underactive Bladder is a symptom complex suggestive of detrusor underactivity and is usually characterized by prolonged urination time with or without a sensation of incomplete bladder emptying, usually with hesitancy, reduced sensation on filling, and a slow stream.
Underactive Bladder Syndrome is a chronic, complex and debilitating disease which affects the urinary bladder with serious consequences. Patients with an underactive bladder can hold unusually large amounts of urine but has a diminished sense of when the bladder is full and is not able to contract the muscles sufficiently and as forcefully as it should, resulting in incomplete bladder emptying.
The symptoms and severity of underactive bladder vary from one person to another and the course of the disease is often unpredictable.
Scientists are working diligently to understand what biological factors contribute to underactive bladder pathogenesis. The most common risk factors associated with this syndrome are:
Damage to the peripheral nerves of the bladder by congenital, inflammatory, neoplastic or traumatic lesions may cause the sensation of bladder filling to be absent or reduced, and large volumes of urine may accumulate, which causes difficulty in emptying the bladder.
High blood sugar causes damage to peripheral nerves supplying bladder wall. Normal urination relies on the synergy between bladder contractions and bladder neck opening. When this is interrupted, such as diabetic patients, the result is incomplete bladder emptying with significant residual volumes.